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Additionally, McConkey et al., in 1967, observed the occurrence of transparent skin that was associated with a decrease in dermal collagen in postmenopausal women [21]

In summary, centromere inactivation accelerates aging through epigenetic disorders, inflammatory cascades, and genomic instability

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Inflammatory cells, such as macrophages, lymphocytes and eosinophils, have previously been reported to be closely associated with the inflammatory processes in asthma (40,49)