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doi: 10.1002/cche.v100.1 54 XieY.WangC.HaoZ

Nervous System: Neural regeneration benefits from neuroprotective effects that mitigate damage after traumatic brain or spinal cord injuries

Furthermore, when apoptosis and necroptosis fail to occur, caspase-8 can be involved in the activation of caspase-1 and inflammasome to trigger pyroptosis, a strongly proinflammatory cell death modality associated with the release of IL-1 and IL-18 [145, 146]

Hudson VM

Source data are provided with the paper

Thus, GSH depletion in vivo increases the hepatic MGO accumulation by impairing its GSH-dependent, GLO-mediated detoxification to d-lactate independent of oxidative stress [76]