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Breakthroughs in these areas require deep interdisciplinary collaboration between structural biology, synthetic chemistry, and clinical needs, balancing efficacy, safety, and accessibility to fill the gaps in antifungal therapy

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Several modifications have been made to mRNA display methods in order to address these limitations, including the use of cDNA display, 606,607 transcription-translation coupled with association of puromycin linker (TRAP) display, 608 cDNA TRAP display, 609 and click display

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Sidrauski, C., Brickner, J