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Research overwhelmingly describes the safety of GHK-Cu positively, such as when the authors of a 2018 review called it a safe, inexpensive, extensively studied compound.14 However, even though copper peptides have demonstrated an impressive safety track record in studies, there are (as with most skin care actives) a few safety risks to consider

They don't just hope for the best

It is generally linked to a lack of B12 or an iron deficiency

This can happen with or without anaemia

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These are very effective at raising blood levels of vitamin B12, thus preventing or reversing a vitamin B12 deficiency