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This timeline mirrors the general pattern seen with other weight loss peptides

[17] Lenler-Petersen P, Hansen D, Andersen M et al

Tiffon C

436 Recent work reveals that some Zur proteins harbor a pair of regulatory Zn II sites distinct from the central HHxHx 2 Cx 2 C motif ( vide supra ) that stabilizes an oligomeric assembly of three or more Zur dimers on the promoters of genes encoding cognate metal efflux transporters, leading to RNA polymerase recruitment and activation of transcription when metal levels become very high

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Some of the targets identified in silico have been already tested, and they reveal various level of effectiveness (Salillas and Sancho 2020)