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Thus, despite significant progress in understanding cancer chemoprevention through dietary agents, much remains to be elucidated about the effects of ITC and Se on epigenetic alterations and antioxidant enzyme expression at different stages of colorectal carcinogenesis, and about their importance as mechanisms by which diets may modulate gene expression and attenuate (or in some cases exacerbate?) cancer progression

For 5-Amino-1MQ, this might include tracking changes in body weight, fat mass, glucose levels, insulin sensitivity, and markers of NAD+ metabolism

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Dietary polyphenols may affect DNA methylation