TIBC, Total iron-binding capacity (TIBC)
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By acting as a carrier for TPL, liposomes further enhance its pharmacokinetics compared to free TPL, extending the drugs in vivo duration, significantly reducing toxicity, and markedly improving therapeutic effects through a controlled release mechanism ( via the enhanced permeability and retention (EPR) effect, as well as an appropriate size that minimizes renal excretion and filtration by interendothelial cells ( in vitro release characterized by a typical biphasic phenomenon, consisting of an initial burst release followed by sustained release
Because Semax has a known molecular weight (about 813.9 g/mol), a stated milligram amount corresponds to a specific molar quantity, and the intranasal solution strengths (0.1% and 1%) map onto the mg/mL anchors used throughout this article
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