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Bioidentical forms of B12, including methylcobalamin, adenosylcobalamin, hydroxocobalamin, are preferred over cyanocobalamin because of better bioavailability and safety

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Mechanistically, this beneficial effect seems to be mediated by the regulation of intracellular Ca 2+ levels by the modulation of calbindin expression, which is associated with calcium homeostasis and plays a role in the protection of dopaminergic neurons in the pathogenesis of PD (Liu et al., 2014)

PubMed Kang YA et al