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Oxidative stress, an imbalance between the production of reactive oxygen species (ROS) and a cells antioxidant defenses, is associated with human diseases as well as aging

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Kaushal V, Dye R, Pakavathkumar P, Foveau B, Flores J, Hyman B, et al

In addition, clustering analysis of GPX genes showed that GPX2, 3, 5, 6 , and 8 demonstrate relatively similar expression profiles compared to those of GPX1, 4 , and 7

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As rainwater enters the groundwater system it dissolves minerals from the soils and rocks, adding hardness and raising the pH