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These modifications enhance the peptide's stability and resistance to enzymatic degradation, particularly by the enzyme DPP-IV (dipeptidyl peptidase IV), thereby slightly extending its half-life compared to Sermorelin (the unmodified GHRH 1-29)

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LB: Conceptualization, Writing original draft, Writing review & editing

Since Prx2 is localized on/next to the membrane, these data suggest that with regard to SOD 1, scavenging of hydrogen peroxide in proximity to the membrane is more important than the interception of cytosolic hydrogen peroxide (106)

In one non-limiting example, the mucoadhesive agent is maltodextrin and/or an alginate gum