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In 1979, believing oxidative stress could be a major factor causing neuronal death in PD, Dr

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& Dogan, M

This peptide was isolated in Zurich by Rinderknecht and Humbel on the basis of its insulin-like activity, but was renamed IGF-1 when it became apparent that its growth-promoting properties were more important than their insulin-like activities (Rinderknecht & Humbel, 1978)

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