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It will require clinical trials by independent entities to delineate the true effectiveness and side effect profile of this and all new medications. Following the results of earlier trials, Novo Nordisk submitted a New Drug Application to the Food and Drug Administration (FDA) in December 2025 for the use of CagriSema to assist and maintain weight loss alongside diet and exercise adjustments

Cualquier persona con antecedentes personales o familiares de cnceres sensibles a hormonas prstata, mama, colorrectal debe considerar el IGF-1 LR3 contraindicado

These findings remain preclinical , meaning they have largely been observed in laboratory and animal studies rather than human clinical trials

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