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It functions as an essential electron carrier within metabolic pathways and serves as a substrate for multiple enzyme systems involved in cellular regulation

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In terms of selecting the formulation delivery device, in a human study with a whole-virus influenza liquid vaccine without adjuvant, the immune response was better when using the breath-powered Bi-Directional OptiNose device and nasal drops in the delivery, rather than traditional nasal spray and an oral spray [22]

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[PubMed] [Google Scholar] Alessio MD, Cerella C, Amici C, Pesce C, Coppola S, Fanelli C, De Nicola M, Cristofanon S, Clavarino G, Bergamaschi A, Magrini A, Gualandi G, Ghibelli L