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The simulations suggested that quinone metabolism yielded an increase in ROS (O 2 . and H 2 O 2 ), producing a maximum of 0.42 M and 1 10 3 M respectively

Association of Smoking, Nicotine Dependence and BDNF Val66Met Polymorphism with BDNF Concentrations in Serum

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Consequently, these altered metabolic profiles might modulate the circulating immuno-inflammatory responses that accelerate inflammation in the CNS

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Thus, in these circumstances GSH, by subtracting biological active NO, could impede the activation of a more effective antioxidant response, which is involved in the increased lifespan