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Research protocols should account for receptor sensitivity, IGF-1R expression levels in the model system, exposure duration, signaling saturation thresholds, dose-response behavior, and peptide stability under laboratory conditions

A large observational study of GP practice data and fluoride levels in drinking water

Candida overgrowth is one of the primary drivers of intestinal hyperpermeability (leaky gut), as hyphal penetration of epithelial cells physically dismantles tight junction proteins

[PubMed: 3485650] 435

Science 273 , 974977 (1996)