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Madsen P, Rasmussen HH, Leffers H, Honor B, Dejgaard K, Olsen E, Kiil J, Walbum E, Andersen AH, Basse B, Lauridsen J, Ratz G, Celis A, Vandekerckhove J, Celis J: Molecular cloning, occurrence, and expression of a novel partially secreted protein "psoriasin" that is highly up-regulated in psoriatic skin

But there are several obstacles to the development of this senolytic approach such as the long-term effect of CAR-T cells therapy with possible aspecific toxicity in different organs 56 , the cost and the difficulty during process development 57 or the selection of non-exhausted T cells to generate efficient therapy 58,59

Safety Profile and Considerations BPC-157 demonstrates a favorable safety profile in both animal research and accumulated user experience

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Amylin signaling plays an important role in satiety pathways and gastric motility regulation