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A MTHFR mutation leads to a shortage of the active form of folate within the body and negatively impact the conversion of homocysteine to methionine

doi: 10.1016/j.ydbio.2012.06.020

[13] NAD+ plays a central role in cellular energy metabolism and is required for the proper function of mitochondria

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In certain embodiments, the viscosity of the gel is in the range from about 100 to about 50,000 cP, about 100 cP to about 1,000 cP, about 500 cP to about 1500 cP, about 1000 cP to about 3000 cP, about 2000 cP to about 8,000 cP, about 4,000 cP to about 50,000 cP, about 10,000 cP to about 500,000 cP, about 15,000 cP to about 1,000,000 cP