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Nonetheless, when extracellular HSP70 is continuously elevated, it stimulates inflammation, oxidative stress, reduced expression of HSF-1, and possibly reduced intracellular HSP70 [91]

The expression level of neurexin-1 increased with age, neurexin-3 remained stable, and neurexin-2 was higher than neurexin-1 and neurexin-3 at the early stage, but intermediate between neurexin-1 and neurexin-3 at the later stage [66]

Nutritional approaches that support circadian and neural health include diets rich in whole foods, omega-3 fatty acids, magnesium, and antioxidant nutrients from vegetables, berries, and nuts

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Figure S3: Primary neutrophil viability is not affected by 5M sulphoraphane (SFN) treatments for 16 hours measured by trypan blue exclusion

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