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When used with pemetrexed, B12/folic acid therapy further increases sub-G1 populations in human adenocarcinoma and large-cell carcinoma cell lines, independent of p53 status (28)

Oral Supplements Work Well For: People with healthy digestive function using B12 supplementation preventatively rather than correctively often achieve adequate results with oral forms

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Contains benzyl alcohol, toxic for neonates and infants

Vitamin B12 is water-soluble and has a low potential for harm, but more injections is not automatically better

doi:10.3389/fneur.2020.570989