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IDO Upregulates Regulatory T Cells via Tryptophan Catabolite and Suppresses Encephalitogenic T Cell Responses in Experimental Autoimmune Encephalomyelitis

These protective benefits have been observed in the GI tract, liver, cardiovascular system, and brain [20, 36]

Reduction of inflammation markers

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This includes patients with acute muscle strains, tendon irritation, ligament sprains, plantar fascia irritation, Achilles tendinopathy, patellar tendinopathy, rotator cuff irritation, tennis elbow, golfers elbow, or localized joint-adjacent soft-tissue pain