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By employing a -adrenergic receptor blocker and a ghrelin receptor antagonist, they discovered that the oral intake of hydrogen water activates the -adrenergic receptor signaling pathway in the stomach, inducing ghrelin secretion, which in turn protects dopaminergic neurons in MPTP-induced PD model mice

Regulation of skin cell behavior and extracellular matrix homeostasis Keratinocytes in the epidermis and fibroblasts in the dermis are the primary cell types responsible for synthesizing and degrading the extracellular matrix (ECM) in the skin

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this study suggested IH as a novel chemotherapeutic agent [115]