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You can read the abstract of this article at Tesofensine (TE) is a weight-loss medication that works by blocking the reabsorption of certain chemicals in the brain

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A few remarks can be made regarding the limitations of this study

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100 g of chopped skeletal muscle was blended with ~400 ml of homogenization buffer (50 mM Tris pH 7.5, 0.5 mM PMSF) for 90 s and spun down for 7 min at 2000 x g