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You can read the full article at Insomnia Caused by Serotonin Depletion is Due to Hypothermia Serotonin (also known as 5-HT) neurons were initially believed to promote sleep based on early studies using a drug called para-chlorophenylalanine (PCPA)

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Methylsulfonylmethane protects against ethanol-induced brain injury in mice through the inhibition of oxidative stress, proinflammatory mediators and apoptotic cell death

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Here we used the latter property to monitor the oxidative and reductive half-reaction