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GHK-Cu is predominantly found in saliva, blood, and urine, and has multiple biological actions when administered to test subjects, including [1]: Antioxidant gene activity [2] Suppression of inflammatory cytokine interleukin-6 [2] Increased protein accumulation [3] Increased collagen synthesis [3] In animal models, GHK-Cu has been shown to increase an anti-inflammatory proteogly called decorin that can protect diabetic rats from kidney-damaging fibrosis [2, 4]
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Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature myeloid-derived immune cells that play a prominent role in driving immune suppression and limiting the response to immunotherapies (3, 4)
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Lienhard, D
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