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The Sirt1/PGC-1 pathway is one mechanism through which NAD+ exerts its protective effects, highlighting its potential as a therapeutic target

Sikiric P, Seiwerth S, Rucman R, Kolenc D, Vuletic LB, Drmic D, Grgic T, Strbe S, Zukanovic G, Crvenkovic D, Madzarac G, Rukavina I, Sucic M, Baric M, Starcevic N, Krstonijevic Z, Bencic ML, Filipcic I, Rokotov DS, Vlainic J

In such cases, intramuscular injections may be a better choice

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