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They are essentially molecular counterparts of each other but are in fact different molecules

157,158 Activation of the insulin or Insulin-like Growth Factor 1 (IGF-1) receptor can enhance insulin sensitivity, improve glucose absorption and utilization by cells, and potentially have positive effects on cardiovascular health and long-term energy balance

Park et al., 2021)

rickettsii is the causative agent of Rocky Mountain spotted fever (RMSF), a disease characterized by fever of over 104 F, maculopapular rash, severe headache, and in some cases death 2

A., Sillitoe, I., Thanki, N., Thomas, P