IF enhances mitochondrial biogenesis and reduces oxidative stress through the activation of AMPK and SIRT1 pathways, thereby protecting neurons from oxidative damage (23, 24, 50)
However, as we age, studies show we lack cysteine and glycinetwo key building blocks of glutathione (18)
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Also, a Beclin-1-interacting protein Ambra1 is dissociated from Bcl-2 following autophagy induction leading to the activation of autophagy (Li et al
[DOI] [PMC free article] [PubMed] [Google Scholar] 131.Lomonosova Y.N., Kalamkarov G.R., Bugrova A.E., Shevchenko T.F., Kartashkina N.L., Lysenko E.A., Shvets V.I., Nemirovskaya T.L