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Methionine, in the form of S-adenosylmethionine (SAM), is required for many methylation reactions, including DNA methylation

How B12 Injections Work Injections deliver B12 directly into the muscle, sending it straight into the bloodstream

Therefore, older individuals might require more frequent B12 injections to maintain optimal levels compared to younger counterparts

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Hydroxocobalamin, in particular, is retained in the body longer than cyanocobalamin, which can reduce the frequency of repeat injections

Banting FG, Best CH, Collip JB, Campbell WR, Fletcher AA: Pancreatic extracts in the treatment of diabetes mellitus