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Clinical trials have shown that Vitamin C is gastroprotective and attenuates non-steroidal anti-inflammatory-drug-induced gastric damage

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This was accompanied by a reduced distribution of these proteins at the plasma membrane and an increase in IEC permeability

The development of the present therapeutic medicines in clinic mainly targets the discovered pharmacological targets, mainly focusing on the key receptors or enzymes

doi: 10.1016/j.numecd.2019 167 SeriniSCassanoRFacchinettiEAmendolaGTrombinoSCalvielloG

Individuals who have undergone gastric surgery (including bariatric procedures) or ileal resection have permanently reduced absorption capacity