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Every escalation decision is reviewed by an independent Safety Review Committee, which evaluates all available data against predefined stopping rules

4.1 Ferroptosis in cerebral ischemia Stroke, also known as cerebral ischemia, is a leading cause of global mortality and disability

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The optimum time to induce ECD by starvation was 96 h since a decrease in angiogenic and migratory capabilities, as well as an increase in recognized markers of senescence, such as -galactosidase, were observed [116]

doi:10.1038/s42255-023-00917-5