Prx and GPx have peroxidase activity in thioredoxin (Trx)- and glutaredoxin (Grx)-dependent manners, respectively [37] (Figure 1)
J Hepatol 2010
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IL-1 and TNF are also responsible for endothelial adhesion and emigration of leukotriene into the tissues, where they activate neutrophils and produce inflammation, loss of functioning, and tissue damage
This balance is regulated by an enzyme called glutathione peroxidase, which is especially important for the thyroid
It contains L-glutathione, an important tripeptide present in the liver