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Reductive stress and mitochondrial dysfunction: the hidden link in chronic disease

The presence of the second active-site cysteinyl residue in PfGrx improves the reactivity of the ternary complex but does not form an intramolecular disulfide bond in contrast to a dithiol mechanism

PLoS ONE 8 , e63952 (2013)

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However, testosterone is not an approved stand-alone treatment for major depressive disorder, and increasing testosterone above a healthy physiological range is unlikely to provide add

doi: 10.1016/j.phrs.2007.04.016 23 WilliamsMDNadlerJL