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Furthermore, nicotine is not only significantly decreasing the testicular activity of androgenic enzymes including testicular steroidogenic acute regulatory (StAR) protein resulting in decreased intratesticular and plasma testosterone and gonadotropin concentrations, but also reduced the testicular levels of glutathione, activities of antioxidative enzymes and mitochondrial membrane potential in testicular cells
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The Order follows that company's conviction in January 2025 for six offences of selling vapes to under-18s during Trading Standards' test purchasing exercises
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