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A study indicates that regular overdose of isolated vitamin B12 supplements, especially among male smokers, may increase the risk of lung cancer (Brasky et al., 2017)

The impact on other biological parameters was minimal

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The therapeutic effect is entirely PepT1-dependent

The administration of 5-LOX or LTB4 inhibitors significantly delays hepatocyte proliferation

Effect of NF-B signaling on apoptosis in chronic inflammation-associated carcinogenesis