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We suspect that this ability to extend the reward only enhances the drugs ability to reinforce smoking. It may also provide a new target for drugs designed to help people stop smoking by interfering with nicotines effects.

To compare the effects of e-cigarette vapor and 3R4F cigarette smoke on BEAS 2B cells, previous studies indicated that when 3R4F cigarette smoke was diluted 500 times, cell viability reached approximately 80%, comparable to cell vitality observed when ECS was diluted five fold 31