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This effect is often seen in chronic smokers who have developed a tolerance to nicotine

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Its lost time, and if Audrey gets seriously hurt or even killed during that period, I can imagine Cooper would never forgive himself

The prospect of criminalising nicotine consumers, people who are disproportionately concentrated amongst lower socio-economic groups and who have been priced out of the legal nicotine market, risks further entrenching disadvantage and is similarly unpalatable

Future studies will focus on understanding the effects of long-term exposure of nicotine.