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Dry Eye Disease Dry eye is a multifactorial disease characterized by ocular dryness, discomfort, pain, and tear film instability

An in vitro study revealed that AGEs binding to RAGE on macrophages and microglia promote oxidative stress by activating NF-KB, and MAPK, c-Jun N-terminal kinase (JNK), and p21RAS signaling pathways (197)

Meditation, for example, encourages mindfulness and can quiet racing thoughts