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The major active component in betel nut, arecoline, leads to addiction by modulating the cholinergic, dopaminergic, and glutamatergic systems, with the involvement of the gut-brain axis and immune-inflammatory responses

Because Zyban contains the same active ingredient as the antidepressant Wellbutrin (bupropion), the FDA encourages people who use Zybanand those who are considering itto talk to their health care providers about the risks of treatment with antidepressant medicines

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95 Self-employed individuals are not eligible for HRAs

Halbert SA, Tam PY, Blandau RJ