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Nicotine consumption via tobacco smoking has almost a built-in limit, because most people do not smoke indoors the need to go outside imposes friction on ones ability to consume nicotine

doi: 10.1016/j.fct.2007.12.007

Moreover, in human small airway epithelial cell lines (HSAEpiCs), uPA and uPAR inhibition can block CSE-induced EMT by reversing the expression of E-cadherin and -catenin and delaying the induction of N-cadherin and Vimentin [174, 175]

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125 In order to rebut a prima facie case, therefore, the responding member must establish (i) that the "urgent circumstances" referred to in Article 2.10 of the TBT Agreement surrounded the adoption of the technical regulation at issue

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