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When exposed to high levels of microplastic pollution, earthworms can carry MPs on their skin through a process known as cutaneous transportation 72

Another study showed that longer chronic exposure (18 months) to IQOS indicated lower toxic effects than CS on respiratory tract histology, lung inflammation, emphysematous changes, oxidative stress responses, and xenobiotic metabolism 68

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Chronic and acute tolerance to subjective effects of nicotine

Concerns on potential gateway effect E-cigarettes and vaporisers may cause non-smokers, particularly youths, to become addicted to nicotine, and serve as a gateway to experimentation and regular use of cigarettes later on

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