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CB-839 treatment increased mitochondrial SOX in both cell lines at relatively low concentrations, starting at 10 nM for the HG-3 cell line and 100 nM for the MEC-1 cell line

At concentrations achievable only through intravenous administration, vitamin C acts differently in the body than the doses obtainable through oral intake

We extended the analysis to human PBMCs, CD14 + monocytes, macrophages, and PMA-differentiated THP-1 cells and detected basal expression in all (Fig

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