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If methylation is sluggish (often for genetic reasons) or the body doesn't have enough nutrients (including vitamin B12 and folate) to turn the methylation cycle, the body can't make enough glutathione
Warm vial to room temperature before injection (cold solutions hurt more)
doi:10.1016/j.biocel.2007.06.005
Temsirolimus is unlikely to reach the clinic because it has devastating side effects even with acute administration, having its use likely restricted to the oncology field [270]
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