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Clinically, bipolar disorder often initially presents with a major depressive episode, with its defining feature, mania, only emerging after months or years, resulting in considerable delays 5

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History [edit] Romeo y Julieta, originally famous for its premium Cuban cigars, expanded production to include cigarettes in 1999

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The campaign promotes a proposal (which was published in the British medical journal Tobacco Control ) to prevent the supply of tobacco to Singaporeans born from the year 2000 which would result in a gradual phasing-out of tobacco in Singapore