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Furthermore, acute exposure of isolated mouse islets or INS-1(832/13) -cells to the oxidative stressors, arsenite, 4-hydroxynonenal, or methylglyoxal, decreased insulin secretion ( Circulating metabolites, like -hydroxybutyrate that enter cells and increase NADH and ROS production in -cells, increase insulin secretion (Figure 6A)
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[26] Ding Y, Fromm M & Avramova Z (2012) Multiple exposures to drought train transcriptional responses in Arabidopsis
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