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The primary receptacle or secondary packaging must be capable of withstanding, without leakage, an internal pressure producing a pressure differential of not less than 95 kPa (0.95 bar, 14 psi) in the range of -40 C to 55 C (-40 F to 130 F)

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Interleukin-1 and Interleukin-8 in Nicotine- and Lipopolysaccharide-Exposed Gingival Keratinocyte Cultures