Similarly, in another part of the study, animals were grouped into four groups, with Group I (animals receiving tween 80), Group II (Diabetic rats without any treatment), Group III (Administration of Sitagliptin at 70mg/kg,p.o), Group IV (Combined therapy of Sitagliptin and Quercetin)
In addition, downregulation of Cx43 (also known as gap junction protein alpha 1, GJA1) expression restored the level of SLC7A11, inhibited ferroptosis and ultimately alleviated cisplatin- and LPS-induced AKI [174]
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J Microbiol Biotechnol, 2023;34(1):17