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Moreover, in fresh samples from patients who underwent neoadjuvant chemotherapy, the GSH/GSSG levels in the resistant group were significantly higher than those in the sensitive group, which is consistent with previous research [28]

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A subsequent increase in intracellular glucose-6-phosphate (glucose 6-P) results in high intracellular glucose concentrations and decreased glucose uptake by muscle and fat

As expected, the expression levels of SREBF1 and PLIN2 were increased by GSTM2 knockdown and decreased by GSTM2 overexpression (Fig