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[52] Stimulation of the brain [edit] Nicotine is a parasympathomimetic stimulant [8] that binds to and activates nicotinic acetylcholine receptors in the brain, [9] which subsequently causes the release of dopamine and other neurotransmitters, such as norepinephrine, acetylcholine, serotonin, gamma-aminobutyric acid, glutamate, endorphins, [10] and several neuropeptides, including proopiomelanocortin-derived -MSH and adrenocorticotropic hormone

Withdrawal from Nicotine When you quit smoking youll probably experience some degree of withdrawal

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Dopamine is a neurotransmitter that the brain releases when the pleasure center is triggered

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