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Public health advocates note that the Unified Agenda is not binding, and they say they hope the Biden administration will reconsider any potential delays and publish the rule as quickly as possible

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[21] A 2014 study tested 55 chemicals in e-cigarette aerosol for both Blu and SKYCIG devices and found acrolein, acetaldehyde, and propionaldehyde at amounts 86 to 544 times less than in cigarette smoke

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For sensitivity analysis, three different methods were applied: convergence testing during the probabilistic simulation, application of a factor to consider drug tolerance and comparison with human toxicological thresholds for some of the agents

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