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Free Radic Biol Med 21:669681 Poli G, Leonarduzzi G, Biasi F, Chiarpotto E (2004) Oxidative stress and cell signalling

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Current American Lung Cancer guidelines recommend the scan for people over 50 who have a 20-pack-year history with a pack-year being defined as "equal to smoking 1 pack (or about 20 cigarettes) per day for a year." But roughly 20% of lung cancer cases are in non-smokers, and women who have never smoked account for two-thirds of those cases

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The decision was immensely controversial and must be considered one of the key events that precipitated the Civil War

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